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Revenue at Shopee, Sea’s e-commerce division, grew by 35.8% last quarter, yet the division’s cost of revenue rose by 43.2% over the same period; Sea blamed “an increase in logistics costs as orders volume grew.”
The next year, PacBio developed a new method to allow multiple sequencing passes on the same DNA molecule. Double stranded DNA templates were ligated to two single stranded adapters, creating what the company called a “SMRTbell template.” Sequencing began at a primer on one of the adaptors and could proceed multiple times per molecule due to circularization, in a process called rolling-circle amplification. This helped reduce PacBio’s error rates significantly.，这一点在体育直播中也有详细论述
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