This was not the first time that microbiologists experienced problems with agar. A phenomenon called “The Great Plate Count Anomaly” baffled researchers in the early 20th century when they observed that the number of cells seen under a microscope didn’t match the actual number of colonies growing on an agar plate. Investigating this discrepancy, researchers found agar itself to be the culprit: when nutrient broths are heated with agar during boiling, harmful byproducts (hydroperoxide) can form due to the reaction of agar with phosphate minerals contained in the media. Researchers can avoid this by autoclaving agar separately from the nutrient broth, or by reducing the amount of agar used.
Nature, Published online: 24 February 2026; doi:10.1038/d41586-026-00530-y
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·乌普萨拉大学教授Emily Holmes领导了这项新研究，着手点主要是影响PTSD发病的重要因素之一的“侵入性记忆”展开，提出了采用“Imagery Competing Task Intervention（图像抵触进程干预）”的治疗思路。
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